Bleomycin Powder For Solution For Injection

Warnings

Black Box Warnings

Severe idiosyncratic reactions including hypotension, confusion, fever, chills, and wheezing occurring usually after the first or second dose have been reported.

Monitoring is very important after administering these doses.

Pneumonitis that progresses to pulmonary fibrosis is the most severe toxicity reported. Risk increases in elderly persons and with doses >400 units.

The drug should be administered under the supervision of an experienced cancer chemotherapy physician.

Contraindications

Hypersensitivity

Concomitant use of bleomycin with brentuximab because of pulmonary toxicity

Cautions

Use cautioin in renal impairment

Hepatic toxicity reported

Use caution when administering oxygen during surgery (increases risk of pulmonary toxicity)

Risk of pulmonary fibrosis (at lower doses if used with other antineoplastics)

Avoid pregnancy

Usage in Pregnancy

Pregnancy Category D

Bleomycin can cause fetal harm when administered to a pregnant woman. It has been shown to be teratogenic in rats. Administration of intraperitoneal doses of 1.5 mg/kg/day to rats (about 1.6 times the recommended human dose on a unit/m2 basis) on days 6 to 15 of gestation caused skeletal malformations, shortened innominate artery and hydroureter. Bleomycin is abortifacient but not teratogenic in rabbits at intravenous doses of 1.2 mg/kg/day (about 2.4 times the recommended human dose on a unit/m2 basis) given on gestation days 6 to 18.

There have been no studies in pregnant women. If bleomycin is used during pregnancy, or if the patient becomes pregnant while receiving this drug, the patient should be apprised of the potential hazard to the fetus. Women of childbearing potential should be advised to avoid becoming pregnant during therapy with bleomycin.

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Product Summary

Bleomycin is used to treat cancer. It works by slowing or stopping the growth of cancer cells. It Used in the treatment of squamous cell cancers, melanoma, sarcoma, testicular and ovarian cancer.

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Frequently Asked Question

This section displays common question about Bleomycin Injection.

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Bleomycin Injection Image Gallery

Bleomycin is used to treat cancer. It works by slowing or stopping the growth of cancer cells. This medication may also be used to control the build-up of fluid around the lungs (pleural effusion) caused by tumors that have spread to the lungs.

Bleomycin Solution For Injection

How to use Bleomycin / Drug Interactions

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Dosing & Uses

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Adverse Effects

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Pharmacology

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